专利名称:ANTIBODIES TO HUMAN PROGRAMMED
DEATH RECEPTOR PD-1
发明人:Gregory John Carven,Hans Van
Eenenneem,Gradus Johannes Dulos
申请号:US13719763申请日:20121219
公开号:US20130108651A1公开日:20130502
摘要:Antibodies which block binding of hPD-1 to hPD-L1 or hPD-L2 and their variableregion sequences are disclosed. A method of increasing the activity (or reducingdownmodulation) of an immune cell through the PD-1 pathway is also disclosed.
申请人:MSD OSS B.V.
地址:Oss NL
国籍:NL
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