专利名称：Alpha-N-methylation of amino acids发明人：Moss, Jason, A.,Swistok, Joseph申请号：EP09157585.2申请日：20090408公开号：EP2110380A1公开日：20091021
摘要：The present invention is directed to a method for ?N-methylation of aminoacids suitable for on-resin methylation, compatible with Fmoc/tBu SPPS, and compatiblewith amino acids bearing protected or unprotected nucleophilic side-chains, notablyArg(Pbf), Met, Cys, and Trp. The present invention is further directed to a compound ofFormula I wherein m, n, X and Y are defined as described herein.α
申请人：F. Hoffmann-La Roche AG
地址：Grenzacherstrasse 124 4070 Basel CH
国籍：CH
代理机构：Küng, Peter
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