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4(R)-substituted 6(S)-phenoxymethyl-, 6(S)-beta-ph

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专利名称:4(R)-substituted 6(S)-phenoxymethyl-, 6(S)-beta-phenylethyl- and 6(S)-beta-styryl-tetrahydropyran-2-ones, a highlystereoselective process for their

preparation, pharmaceutical preparationbased on these compounds and their use

发明人:JENDRALLA, HEINER, DR.,BECK, GERHARD,

DR.,WESS, GUENTHER, DR.,KEREKJARTO,BELA, DR.

申请号:EP87106522.3申请日:19870506公开号:EP0244833B1公开日:19920624

摘要:4(R)-substituted 6(S)-phenoxymethyl-, 6(S)- beta -phenylethyl- and 6(S)- beta -styryltetrahydropyran-2-ones of the formula V …… in which R<7>, R<8> and A have themeanings indicated, the corresponding open-chain hydroxycarboxylic acids, and theirpharmacologically tolerable salts and esters are used as medicaments. Novel alpha , beta-unsaturated lactones for the preparations of the compounds of the formula V areadditionally described.

申请人:HOECHST AKTIENGESELLSCHAFT,HOECHST AKTIENGESELLSCHAFT

地址:POSTFACH 80 03 20; W-6230 FRANKFURT AM MAIN 80,POSTFACH 80 03 20; W-6230 FRANKFURT AM MAIN 80

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