专利名称:Neisseria meningitidis serogroup B
glycoconjugates and methods of using thesame
发明人:Robert Seid申请号:US103349申请日:20030819
公开号:US20040052805A1公开日:20040318
摘要:The present invention pertains generally to novel serogroup B glycoconjugates.More particularly, the invention pertains to glycoconjugates formed from a serogroup Bcapsular oligosaccharide derivative (MenB OS derivative) in which sialic acid residue N-acetyl groups are replaced with N-acyl groups. The invention also pertains to vaccineformulations containing the glycoconjugates, methods of making the vaccineformulations, and methods of using the vaccine formulations to treat or preventserogroup B or K1 disease in a mammalian subject.
申请人:CHIRON CORPORATION
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