Drug treatment of overactive bladder

专利名称：Drug treatment of overactive bladder发明人：Michael E. DiSanto申请号：US15207718申请日：20160712公开号：US09943512B2公开日：20180417

摘要：Provided are methods of treating an overactive bladder in a patient whichinclude: administering a Myosin II ATPase inhibitor compound; or administering an Xgroup and Y group substituted (3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3b] quinolin-4-one) compound of Formula 1 or administering an X group and Ygroup substituted (3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3b] quinolin-4-one) compound of Formula II; or administering pharmaceutically-acceptable salts,racemic mixtures, enantiomers, or prodrugs of said compounds, useful in their active formas inhibitors of Myosin II ATPase related to over-active bladder. Optionally thecompounds are administered intervesicularly into the bladder. Also provided arepharmaceutical compositions comprising said compounds useful in their active form, asmethods of treating a patient suffering from an over-active bladder related to inhibitionof Myosin II ATPase. These pharmaceutical compositions also may contain one or moreother compounds useful in their active form, as methods of treating a patient sufferingfrom an over-active bladder.

申请人：Michael E. DiSanto

地址：Burlington NJ US

国籍：US

代理人：Daniel M. Cohn,Howard M. Cohn

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