专利名称：DIACYLGLYCEROL ACYLTRANSFERASE
INHIBITORS
发明人：BOLIN, DAVID, R.,CHEUNG, ADRIAN, WAI-HING,HAMILTON, MATTHEW,MICHAEL,MARCOPULOUS,NICHOLAS,MCDERMOTT, LEE,APOSTLE,QIAN, YIMIN
申请号：EP09826537申请日：20091027公开号：EP2350311A4公开日：20120530
摘要：Provided herein are compounds of the formula (I): were Rl is phenyl, R2 ishyrogen, halogen or lower alkyl,X is carbon on nitrogen, and R3 is isoquinoline, -amino, ora-4- to 6-membered heterocycloalkyl ring and pharmaceutically acceptable salts thereof,which are active as DGAT inhibitors and therefore find uses in treatment of diseasesassociated with abnormal metabolism of triglicerides, such as, for example, obesity, typeIl diabetes mellitus and metabolic syndrome.
申请人：VIA PHARMACEUTICALS, INC.
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