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COMBINATION THERAPY FOR THE TREATMENT OF CANCER

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专利名称:COMBINATION THERAPY FOR THE

TREATMENT OF CANCER

发明人:WIGGINGTON, Jon, Marc,PANDYA, Naimish,

Bharat,LECHLEIDER, Robert, Joseph,KOENIG,Scott,BONVINI, Ezio

申请号:EP16808255.0申请日:20160609公开号:EP3307240A1公开日:20180418

摘要:This invention relates to a pharmaceutical composition that comprises a firstmolecule that specifically binds HER2/neu and a second molecule that specifically binds acell-surface receptor (or its ligand) that is involved in regulating an immune checkpoint(or the ligand thereof). The invention particularly relates to the embodiment wherein thesecond molecule binds to PD-1. The invention also relates to the use of suchpharmaceutical compositions to treat cancer and other diseases.

申请人:MacroGenics, Inc.

地址:9704 Medical Center Drive Rockville, MD 20850 US

国籍:US

代理机构:Barker Brettell LLP

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