Process for producing cycloalkanone derivatives

专利名称：Process for producing cycloalkanone

derivatives

发明人：Mine, Koji,Fukuda, Kimikazu申请号：EP03029676.8申请日：20031223公开号：EP1433773B2公开日：20170719

摘要：The present invention provides a process for producing 2-(1-hydroxyalkyl)cycloalkanone and/or 2-(1-hydroxyaryl)cycloalkanone in high yield andselectivity, as well as a process using the same to produce a cycloalkanone derivativeuseful as a perfume material and a physiologically active substance. Disclosed is a processfor producing compound (3), which includes subjecting a cycloalkanone, and aldehyde (2)containing carboxylic acid (1), to aldol condensation in the presence of water and a basiccatalyst, wherein the molar amount (referred to hereinafter as A) of the basic catalystadded is not less than the molar amount (referred to hereinafter as B) of the carboxylicacid (1) contained in the aldehyde (2) and the difference between A and B, that is, (A - B) is0.06 mol or less per mol of the aldehyde (2) , as well as a process for producingcompounds (7) and (8) by using the compound (3) obtained by the above process.

申请人：KAO CORP

地址：JP

国籍：JP

代理机构：Hoffmann Eitle

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